Abstract :
Coronary heart disease is continuously increase in India. Acute myocardial infarction (AMI) and unstable
angina are now recognized as part of a spectrum of clinical disease collectively known as acute coronary
syndromes (ACS). The serum cholesterol binding reserve, should be a useful factor for predicting the risk
of coronary heart disease.
Materials and Methods: Subjects who were diagnosed clinically and chemically as CHD patients were
selected out of the patients Gandhi Medical College in department of Cardiology, Hamidia Hospital,
Bhopal. This study was done in 25 controls and 50 cases which were divided sexwise and age wise. There
were 25 controls, 11 females and 14 males. Total coronary arterial diseases cases were 50 in number, There
were 14 males & 11 females in acute coronary syndrome cases and were 14 males and 11 females stable
angina.
Result: The serum cholesterol was higher and SCBR was significantly lower in stable angina
(25.7±7mg%) & acute coronary syndrome (60.2±6.2 mg%) as compared to controls (186.1 ± 27mg%)and
(60.2±6.2 mg%). Lower SCBR the higher tendency to develop atherosclerosis and hence the higher the
risk of coronary heart disease.
Conclusion: It concluded that SCBR and SC maybe considered together as a better biochemical markers
for the risk of atherosclerosis.
Keyword :
Serum cholesterol binding reserve, (SCBR), (ACS) Acute coronary syndrome, Coronary heart disease, (CHD) Stable angina (SA).