Author :
Garima Sharma, Pallavi Sharma, Amit Sharma, Santwana Verma, Prashant Panda, Gaurav Sharma
Volume :
9
Issue :
1
Abstract :
Introduction: Acute viral hepatitis is a systemic infection affecting the liver predominantly. It is common health problem in areas where safe drinking water is not universally available. In recent times we have witnessed frequent outbreaks as a result of that.
Aim: To estimate sero-positivity of Hepatitis A and E viruses in indoor patients of hepatitis, presenting with jaundice using ELISA.
Settings and Design: Blood samples and clinical information were collected from cases of jaundice and referred to VRDL lab for analysis over a period of 1 year.
Materials and Methods : Samples were tested for anti –HAV immunoglobulin M (IgM) and anti –HEV immunoglobulin M (IgM).
Data was entered into a pre-structured data entry form, on Microsoft Excel sheet.
Results: The viral etiology was confirmed in 236 (41.1%) cases while in 337 (58.8%) cases no hepatitis virus could be detected, hepatitis E virus were found to be maximum in 45.76% cases, followed by HAV (39.83% cases)and while in 14.41% cases no hepatitis virus could be detected.
Conclusion: Routine basic microbiological analysis of drinking water should be carried out by assaying the presence of Escherichia coli by the multiple tube fermentation technique.
Keyword :
Hepatitis, Jaundice, ELISA