Abstract :
Aims: To evaluate effect of amniotic membrane grafting on non healing corneal ulcer and incidence of complications and recurrence of disease.
Materials and Methods: This would be an observational study with study period of one year involving 58 randomly selected patients with corneal surface disorder divided into groups, group A, patients control group(medical therapy) and group B, patients the study group (amniotic membrane grafting).
Result: Relief of symptoms was assessed under individual complains of pain, photophobia, foreign body sensation, watering, Redness and discharge. In Group-A out of 28 patients, 24(85.72%) showed complete relief of pain, 25 (89.28%) patients showed complete relief of photophobia, 26(92.85%) patients showed relief of foreign body sensation, 24(85.71%) showed complete relief of watering, 22(78.51%) patients showed complete relief of redness,25(89.28%) showed complete relief of discharge. In Group-B, out of 30 patients, 29(96.6%) showed complete relief of pain, 27 (90%) patient showed complete relief of photophobia 28 (93.33%) patients showed relief of foreign body sensation, 27(90.00%) patients showed complete relief of watering, 28(93.33%) patients showed complete relief, 29(96.6%) showed complete relief of discharge. Statistically the difference is insignificant p
Conclusion: Amniotic membrane grafting definitely gives good symptomatic relief and reepithelialization. Patients having AMG have short operative time and early improvement in symptoms, visual acuity and re-epithelialization than any other method of grafting.
Keyword :
Amniotic membrane grafting, Medical Therapy.