Abstract :
Introduction: Dysfunctional uterine bleeding has been defined as abnormal uterine bleeding not caused
by pelvic pathology, medications, systemic disease or pregnancy. Though it is the most common cause
of abnormal uterine bleeding, DUB is a diagnosis of exclusion. It is typically characterised by heavy
prolonged or profuse flow with or without breakthrough bleeding. It has great variations in endometrial
patterns.
Materials and Methods: A retrospective and prospective study was conducted from January 2016 to
December 2018 involving 240 patients between 20–60 years with symptoms of dysfunctional uterine
bleeding presenting to Annapoorana Medical College and Hospital Salem. Their endometrial samples
were obtained by dilatation and curettage or by endometrial aspiration. To have broader analysis the
endometrial histopathology in hysterectomy specimens where the clinical diagnosis was DUB were also
included. Patients who were registered as inpatients and outpatients with the diagnosis as DUB were
included in the study. Tabulations were made with respect to age, parity, bleeding type and endometrial
histopathology. Clearance from the ethical committee was obtained.
Results: The most common age group in which DUB is seen is 41-50 years group. The prominent bleeding
pattern seen is menorrhagia 49%. Most common endometrial profile was proliferative pattern, seen in 40%.
Next followed by disordered proliferative endometrium in frequency 35.42%. Prevalence of DUB is seen
more in multiparous women.
Conclusion: DUB is seen mainly during 41-50 years age group and majority presented with menorrhagia.
No specific relationship exists between bleeding pattern and histopathological profile. The cause of DUB is
either anovulatory or ovulatory. Anovulatory endometrium was much more common in our study, similar
to other studies.
Keyword :
Dysfunctional uterine bleeding, Menorrhagia, Endometrium, Histopathology.