Abstract :
Background: Fine Needle Aspiration Cytology of the thyroid gland is firmly established as an important test for the evaluation of thyroid diseases and an effective test for the preoperative diagnosis of solitary thyroid nodule.
Aims & Objective: 1. To correlate cytological and histopathological finding in thyroid lesions.; 2. To find out the spectrum of thyroid lesions in our rural hospital.
Materials and Methods: Prospective study of 2 years duration was undertaken in our institution. Total 110 cases were included in this study. All had FNAC examination as an outpatient procedure. Out of 110 cases, 64 were operated and specimens were sent for histopathology.
Result: Out of the 111 patients studied, on cytology 104 were non-neoplastic lesions, 3 were neoplastic, and 3 were inadequate. Out of 111 patients, Histopathology of 65 thyroid specimens showed 28 Colloid/Nodular goiter, 14 Multinodolar goiter, 5 Lymphocytic thyroiditis, 7 Hashimoto’s thyroiditis,1 Granulomatous thyroiditis,3 follicular carcinoma, 1 undifferentiated Anaplastic carcinoma,1 Medullary carcinoma, 1 papillary carcinoma.
Interpretation and Conclusion : By comparing the result of FNAC and histopathology, FNAC had higher accuracy, sensitivity of 80% and specificity 100% in the diagnosis of neoplastic thyroid lesions. FNAC is safe, inexpensive and less invasive diagnostic method with excellent patient compliance. FNAC can be used in the management of thyroid swelling to avoid unnecessary surgery on conditions like thyroiditis. FNAC with the help of imaging techniques is helpful in diagnosis of neoplastic lesion.
Keyword :
Thyroid gland, Fine needle aspiration cytology (FNAC), Histopathology