Stem cells: Isolation, preservation and application in dental surgery


Article PDF :

Veiw Full Text PDF

Article type :

Review Article

Author :

Amit Agarwal, Sakshi Sharma, Yogeshwari Krishnan, Himanshu Aeran

Volume :

6

Issue :

2

Abstract :

In the past few years, third molars have garnered great attention in regenerative medicine as a potential source of pluripotent stem cells. They offer easy accessibility, plasticity coupled with less invasive harvesting procedure in comparison to the traditional sources of stem cell but do not have the ethical issues associated with other sources of stem cells. Various sources of dental stem cells include stem cells from adult human dental pulp like that of third molars, stem cells from human primary exfoliated deciduous teeth, periodontal ligament stem cells, and dental follicle Stem Cells from human third molars. Dental pulp stem cells have mesenchymal stem cell like qualities namely differentiation into multiple lineages and an inherent capacity to renew its own population. When exposed to specific stimuli, these are capable of differentiating into neurons, adipocytes, osteocytes and chondrocytes, etc. hence allowing applications in various systemic illnesses. Dental stem cells appear to retain their stem cell properties following cryopreservation making their storage and mass application easy.

Keyword :

 Stem cells, Dental pulp.
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