Squash cytology- Useful tool to diagnose fungal infection in COVID patient


Article PDF :

View Full Text PDF

Article type :

Original Article

Author :

Snehal Fakira Jumnake, Nilima Dilip Lodha, Kiran S Bharati, Aishwarya Bhongade

Volume :

15

Issue :

2

Abstract :

Objective: This study aims to diagnose fungal infections in post-COVID-19 patients using both squash cytology and histology to minimize morbidity and mortality.Materials and Methods: Conducted at a tertiary medical center over six months, this prospective observational study included hospitalized patients who tested positive for SARS-CoV-1 (COVID-19) and exhibited clinically diagnosed or suspected fungal infections. Representative samples were analyzed using cytological squash smears and histopathology sections, stained with H&E, PAP, MGG, and PAS.Results: Among the 45 patients—34 males and 11 females—35 were diagnosed with mucormycosis through both histology and cytology. Additionally, two patients each were identified with aspergillosis and candidiasis through histology.Conclusion: For prompt diagnosis and management, leading to improved outcomes, squash cytology and histopathology prove to be more efficient and less time-consuming than culture methods.

Keyword :

Squash cytology, Histology, Fungal infections post-COVID-19