Abstract :
Chronic use of tobacco and areca nut is strongly associated with oral squamous cell carcinoma (OSCC), particularly affecting the gingivobuccal sulcus. Due to delayed clinical recognition, it frequently presents at advanced stages, necessitating aggressive multimodal treatment. This case report presents a 58-year-old male diagnosed with moderately differentiated squamous cell carcinoma (SCC) involving the right gingivobuccal sulcus, with perineural invasion and mandibular involvement. The patient underwent partial mandibulectomy, selective neck dissection, and adjuvant radiotherapy. This report highlights the importance of early detection, lifestyle modifications, and a multidisciplinary treatment approach for optimizing outcomes in OSCC.
Keyword :
Gingivobuccal sulcus, Oral squamous cell carcinoma, Perineural invasion, Mandibular involvement, Tobacco-associated malignancy.