Abstract :
Purpose: Fungi have emerged as an important cause of health-care associated infections (HCAI) in last few decades. Candida spp. is the most common cause of invasive fungal infections (IFI) in hospitalized individuals. The present study was conducted in a tertiary care teaching hospital with an aim to study species distribution and antifungal susceptibility pattern of Candida isolates from cases of HCAI..
Materials and Methods: Candida isolates from cases of HCAI from medical intensive care unit were identified up to species level. Antifungal susceptibility testing of Candida isolate was done by Clinical and Laboratory Standard Institute (CLSI) broth microdilution (BMD) method.
Results: The rate of CA-UTI due Candida spp. was 0.3 per 1000 catheter associated days. The rate of catheter related Candida BSI was 0.9 per 1000 catheter associated days. Predominance of non albicans Candida spp. over C. albicans was noted. Fluconazole resistance was significantly high in NAC spp. compared to C. albicans.
Keyword :
Health-care associated infections (HCAI), Invasive fungal infections (IFI), Broth microdilution (BMD), Bloodstream infections (BSI), Catheter associated urinary tract infection (CA-UTI), Catheter related blood stream infection (CR-BSI)