Abstract :
Plan: Development and Validation of a method for the UV simultaneous determination of curcumin and Gefitinib.
Preface: U.V Spectrophotometric method has been widely employed in the determination of individual components in a mixture or fixed dose combination.For the ternary mixture containing Curcumin and Gefitinib, no spectrophotometric method for simultaneous evaluation has been reported so far.Thus our aim is to develop simultaneous equation method for estimation of the ternary mixture using U.V spectrophotometry.
Methodology: The method was validated as per ICHguidelines. The recovery studies confirmed the accuracy and precision of the method.
Outcome: It was successfully applied for the analysis of the drug in bulk and could be effectively used for the routine analysis
Keyword :
Curcumin, Gefitinib, simultaneous estimation, UV spectrophotometric method