Serum magnesium level as a predictive tool for preterm labour


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Article type :

Original Article

Author :

Pradeep Kumar Meena, Sunita Maheshwari

Volume :

7

Issue :

3

Abstract :

Introduction: Serum magnesium level in pregnancy is a valuable tool to find out preterm onset of labour. In the asymptomatic group, greater surveillance and administration of steroids, tocolytics and transfer to a higher centre wherever necessary has to be done with mothers with low serum magnesium level. Spontaneous preterm labor that is labor before 37 weeks of gestation is the main cause of preterm delivery. With increasing gestation the level of Serum magnesium levels decreases. Materials and Methods: A case-control study was carried out to evaluate serum magnesium levels and associated symptoms in women with preterm labour (28-36 weeks) and compare them with patients in same gestational age who delivered at term (37-40 weeks). Results: Women in preterm labour had a significantly reduced serum magnesium level (mean 1.466 mg/dl with a S.D. of 0.077 versus 2.083 mg/dl with a SD of 0.105) for those delivered at normal magnesium levels.(p The serum Magnesium level of preterm patients ranged from 1.32 to 1.60 mg/dl with mean Magnesium level of 1.466 0.077 S.D. In normal pregnant women it ranged from 1.85 to 2.36 mg/dl with a mean Magnesium level of 2.083 0.105 S.D which was highly significant (p Magnesium levels observed between the study population and control population is independent of factors like maternal age, parity, socio-economical status. Conclusion: The present study revealed significantly lower levels of serum magnesium in patients with preterm labour without any apparent cause as compared to normal pregnant women in labour. Hence, estimation of serum magnesium levels in pregnancy may be a useful parameter in preterm labour. The results of the present study add to the existing evidence that low serum magnesium level may be a risk factor for preterm labour.

Keyword :

 Preterm, Serum magnesium level, Term delivery, Parameter.
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