Abstract :
Background: Plummer-Vinson syndrome (PVS) is a triad of dysphagia, iron deficiency anemia and upper esophageal web. Early diagnosis with adequate treatment is necessary to prevent its malignant transformation.
Aim: To represent different clinical pictures of PVS and to evaluate the treatment outcome and determine its prevalence.
Materials and Methods: This is a descriptive study with study population of 267 patients with dysphagia and 40 had PVS. Post cricoid webs were dilated and post-operative iron correction was done. Patients are on regular follow up.
Results: Analysis showed highest incidence in females with dysphagia being the main presenting complaint in all the patients. All had iron deficiency and 90% of patients had post cricoid web.
Conclusion: PVS is a precancerous condition. Serum ferritin should be the preferred parameter for diagnosing iron deficiency anemia. Regular follow up is warranted to prevent malignant progression.
Keyword :
Plummer vinson syndrome, Iron deficiency anemia, Serum ferritin, Malignancy