Abstract :
Background: Blood transfusion saves millions of life in emergency situations and is considered has life saving drug. Blood transfusion is associated with several risks which also includes transfusion transmissible infections. With the implementation of strict donor selection, effective and sensitive screening tests can ensure the least reduction risk of acquiring transfusion transmissible infections. The prevalence of transfusion transmissible infections among blood donors reflect the burden of diseases among particular population.
Aim: The aim of this study is: 1. To estimate the prevalence of transfusion transmissible infections among blood donors in a rural tertiary care centre; 2. To analyse the trends of transfusion transmissible infections over study period.
Results: A total of 21,089 voluntary blood donors were studied. There were 20,356 male donors and 733 female donors with ratio of 28:1. The prevalence of HIV, HBV, HCV, Syphilis and Malaria was found to be 0.14%, 0.82%, 0.02%, 0.13% and 0.03% respectively. The prevalence of HBV was highest (0.82%) followed by HIV(0.14%). Our study also showed decrease in trends of HCV and Syphilis over study period.
There was strong association of transfusion transmissible infections among O positive blood group.
Conclusion: The prevalence of transfusion transmissible infections has decreased over time, hence implementation of strict donor selection criteria and use of sensitive screening tests has lead to decrease in trends.
Keyword :
Transfusion transmissible infections, Sero- Prevalence, Blood donors.