Abstract :
In this study we attempted to design, develop and substantiate a modern contemporary biomarker for epileptic (epilepsy) subjects (patients) neuronal-instability. Initial study is done on 91 subjects through the application of neuronal-unpredictability and/or variability of the marked e-SoZ as a metric to envisage and foresee the epileptic operational (surgical) outcome. the neural-instability predict (42/45) subjects unsuccess with surgery, by a total accuracy of 75% (predictive) when matched with subjective-clinicians accuracy at 49%(results-effective). We differentiate instable zonal areas (zones) which were not diagnosed in unsuccessful cases (i.e., unsuccessful outcomes). While compared with EEG features, the neural-variability outpaced in prognosis strength and, also construal, which support that neuronal delicacy as a bio-marker for the electro encephalography e-SoZ.
Keyword :
Epilepsy, Seizure, Epilepticseizures, Eseizures, Dynamical systems, Delicate nodes, Fragile nodes, Epileptic seizure onset zone, eSoZ