Abstract :
In classical Ayurvedic literature, the root preparation of plant Chitrak (Plumbago-zeylanica) is well documented to be having anti-cancer properties. Away from its use as anti-neoplastic drug, it is also a very common ingredient in so many Ayurvedic formulations which are used as herbal digestive and carminative. Many times they can be prescribed to a pregnant woman also, so the present study is designed to assess the teratogenic effect in mice embryos induced by Chitrak as Ayurvedic medicine. After evaluation of 24 fetuses who have received Chitrakroot powder during their anti-natal life period, it can be said that Chitrak is relatively safe for them; however, only a few fetuses have shown subcutaneous hemorrhages in their necks.
Keyword :
Chitrak, Anti-neoplastic, Janmabalapravrita, Plumbagin, Plumbago-zeylanica, Ayurveda, Teratogenic