Abstract :
Haemophagocyticlymphohistiocytosis (HLH) is an uncommon, life threating and likely underdiagnosed disease of diverse etiologies caused by a defective NK/T- cell cytotoxic pathway resulting in uncontrolled hypercytokinemialeading to end organ damage carrying a high mortality rate. Here we report HLH complicating SLE in a 42 years old female associated with disseminated histoplasmosis and accidentally detected as seropositive for HIV. This is extremely rare in the world literature.
Keyword :
Haemophagocyticlymphohistiocytosis, Histoplasmosis, SLE