Abstract :
Hepatitis-B Virus infections are a serious global and public health problem. To assess the
magnitude and dynamics of disease transmission and for its prevention and control, the study
of its seroprevalence is important. A medical college catering to the needs of a large population
represents an important centre for serological surveys. Available data, on the seroprevalence
of these bloodborne pathogens is also very limited. A study was undertaken to estimate the
seroprevalence of Hepatitis-B Surface Antigen (HBsAg) in both the sexes and different age
groups in a hospital-based population. Serum samples collected over a period of 24 months from
patients admitted to various IPDs of Era’s Lucknow Medical College and Hospital, Lucknow
were subjected within the hospital-based microbiology lab for the detection of HBsAg using
ELISA test. The seroprevalence of HBsAg was found to be 1.92%. The study throws light on the
magnitude of viral transmission in the community in Lucknow city and provides a reference for
future studies.
Keyword :
ELISA, Hepatitis B virus, Seroprevalence.