Abstract :
Study of single cell with respect to its electrical characteristics is a promising noninvasive tool for modelling bio device for early diagnosis of cancer. In this paper, a relative study of cell impedance based on electrical model of a single cell is presented for fabrication of biodevice which will be helpful in distinguishing normal cells from malignant or differentiating cells of same phenotype. The bioimpedance of a cell per unit surface length has been studied and simulated for a range of frequency inputs. The simulation is done in MATLAB environment which shows that the capacitance of the cellular membrane is effective till a particular range of input frequency, after which, the conductivity of cell plays a significant role in governing the permeability of cells.
Keyword :
bioimpedance, MATLAB, electrical model, normal and cancer cells