Abstract :
Introduction: Pre labour rupture of membrane is associated with an increased maternal and perinatal
morbidity and mortality. So confirmatory diagnosis is essential before initiating the definitive treatment of
PROM.
Materials and Methods: This study was a cross sectional, case control, hospital based study. All pregnant
women having gestational age 28 to 42 weeks are divided into 3 groups as per criteria. Each group has
30 pregnant women group 1 and group 2 are the cases studied and group 3 is control group. Data analysis
was done by ANOVA test, kurskal Wallis Test. Difference between two groups are analysed using Man
whitney’s U test.
Results: The level of vaginal fluid urea and creatinine came out to be higher in group 1 (confirmed cases)
than group 2 (suspected cases) and group 3 (controls).
Conclusion: Detection of urea and creatinine in vaginal fluid is easy, safe and cost effective method to
diagnose PROM.
Keyword :
Premature rupture of membrane, Vaginal fluid, Urea, Creatinine.