Role of early indicators in the diagnosis and outcome of neonatal sepsis in tertiary care hospital


Volume :

3

Issue :

1

Abstract :

Sepsis is the commonest cause of neonatal mortality. Septicemia was the commonest clinical category with an incidence of 23 per 1000 live births. Number of screening procedures like micro ESR ,band cell count, I/T ratio, gastric aspirate for polymorphs, C –Reactive protein, alpha haptoglobin, serum fibrinogen levels have been tested in their efficacy of predicting neonatal sepsis. Positive CRP was found to be the single most sensitive and specific test in diagnosis of neonatal septicemia. The present study 180 neonates with clinical suspicion of septicemia included to evaluate the usefulness of combination of tests in septic screen in predicting neonatal sepsis. CRP was positive in 94 cases (91.3%) of culture positivity with statistical significance. Case fatality rate was 26.1%.
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