Volume :

2

Issue :

1

Abstract :

Resistance pattern of cephadroxil monohydrate and ceftriaxone sodium against different clinical isolates was the aim of the study and 90 clinical isolates comprising of Escherichia coli, Staphylococcus aureus, Klebsiella, Proteus and Pseudomonas aerogenosa were collected from different local pathological laboratories and their resistant pattern against cephadroxil monohydrate and ceftriaxone sodium were studied using disc diffusion method. Klebsiella, (86.6% against cephadroxil monohydrate and 53.33% against ceftriaxone sodium) and Proteus (66.67% against cephadroxil monohydrate and 33.33% against ceftriaxone sodium). In case of Staphylococcus aureus and Escherichia coli, resistance found was 41.18% and 48% against ceftriaxone sodium,82.35% and 97.62% against cephadroxil monohydrate respectively and in case of Pseudomonas aerogenosa resistance found was 40% against ceftriaxone sodium and 90% against cephadroxil monohydrate. It is concluded from these figures that microbial resistance against these cephalosporins are increasing in the population which is alarming and therefore it is recommended to physicians to prescribe these antibiotics only if no other alternate is available in clinical practices.