Abstract :
Introduction: Nasal NK/T-cell lymphoma is a rare extranodal large cell lymphoma that involves the nasal
cavity. In majority of cases, Epstein Barr virus is present and Immunophenotype shows CD3 and CD56
positivity. Loco-regional relapse is very common with poor prognosis.
Case Report: We report a case of Relapsed NK cell Lymphoma of the orbit and scalp region in a young
boy with EBV negativity, CD3 negativity and clinically aggressive disease. Despite aggressive treatment,
our case relapsed early and was complicated by prolonged pancytopenia, CNS involvement and patient
died less than one year following diagnosis.
Conclusion: NK cell lymphoma is an aggressive cancer with high mortality. Multidisciplinary modalities
are essential to treat the NK cell lymphoma with radiotherapy, chemotherapy, newer agents, and
hematopoietic stem cell transplantation.
Keyword :
NK/T cell Lymphoma, Immunopheno type, Scalp, Orbit.