Abstract :
Aims and objectives:
Morphological evidence of the
developmental insults has been consistently
documented in schizophrenia patients in the
form of minor physical anomalies (MPAs).
Schizophrenia patients with higher number
of MPAs are considered as a subgroup of
Schizophrenia having clear developmental
basis. But so far no study has found any
specific MPA that is consistently or
exclusively present in this subgroup of
schizophrenia. We analyzed regional MPAs
in schizophrenia patients having higher and
lower number of MPAs and healthy
controls. Methodology:105 schizophrenia
patients and 50, agematched, right-handed
healthy controls were assessed for MPAs
on the Extended Waldrop Scale (EWS).
Patients were median-split into high- (H)
and low-MPA (L) groups based on EWS
scores and were assessed for
psychopathology on positive and negative of ears and PANSS general scores.
Conclusions: Regional specificity of
MPAs in schizophrenia is significant from
a neurodevelopmental point of view.
Prominent forehead and lack of ear lobe
are the specific MPAs which would be
found in the developmentally buttressed
schizophrenia group.
Keyword :
Mona Physcial Anamolies (MPA), Schicophronica.