Volume :
5
Issue :
1
Abstract :
When pulp tissue becomes necrotic in immature teeth, the prognosis of the teeth is compromised. Disinfection of the root presents several challenges including difficulties in cleaning and shaping of large canals with open apices, obturation of canals with open apices, and potential root fractures caused by thin and/or weakened root walls. The regeneration of immature permanent teeth following trauma could be beneficial to reduce the risk of fracture and loss of millions of teeth each year. The purpose of this article is to review these biological procedures and the hurdles that must be overcome to develop regenerative endodontic procedures.