Article type :
Review Article
Author :
Sangeetha S, Padmalochani B, Jaishree Tukaram Kshirsagar, Sai Sarath Kumar Kothimbakkam, Burnice Nalina Kumari C
Volume :
4
Issue :
4
Abstract :
Periodontal disease is a multifactorial disease caused by imbalance between complex microbial community
and the host immune response. Plaque provides favorable environment for the survival and growth of
microorganisms inducing periodontal disease. The current concept of biofilm formation and cell to cell
communication of microorganisms present in the biofilm occurs by the production of chemical signaling
molecules which has become the niche for molecular level research projects. This biological process is
called quorum sensing which modulates the expression of genes involved in survival, biofilm formation,
virulence and pathogenicity of microorganisms. To eradicate this communication, quorum quenchers play
a role in the inhibition of signals of quorum sensing. This review article enlightens the quorum sensing
signaling and the magical action of quorum quenchers from the data collected by different analysis.