Abstract :
Background and Objectives: Bipolar Affective Disorder (BPAD) is a complex, episodic and heterogeneous condition leading to impairment of Quality of life (Qol). The current study was undertaken with the aim to assess the Quality of Life of patients with Bipolar Affective Disorder, compare it with general population and to examine the correlation of socio-demographic and clinical variables with the Quality of Life.
Methodology: This was a cross-sectional case-control study. Hundred consecutive patients diagnosed to have BPAD as per ICD-10 currently euthymic who fulfilled the inclusion and exclusion criteria and gave informed consent were included for the study. Fifty healthy controls were selected from the general population after clinical interview. Subjects were administered YMRS and HAM-D followed by assessment of QoL using WHOQOL-BREF (World Health Organization Quality of Life –Brief version). The data was analysed using SPSS package version 15.0.
Results: Comparison of the four domain scores of WHOQOL-BREF showed that BPAD patients Qol was significantly impaired than the healthy controls (Physical health, p
Conclusion: The emerging body of research has shown that the BPAD has a negative effect on the QoL even during periods of euthymia and remission. A number of socio-demographic and clinical variables have a bearing on the QoL of patients with BPAD.
Keyword :
Bipolar affective disorder, Quality of life, Remission