Purification and Characterization of Riboflavin Carrier Protein from Guinea Pig Serum and Cytotoxic Activity of Its Antisera against Hela Cancer Cells


Article PDF :

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Volume :

10

Issue :

2

Abstract :

In the present work, Riboflavin Carrier protein was purified from Guinea Pig Serum to investigate the cytotoxic activities of antibodies raised against it. The treated cells with different dose of antisera from Guinea pig serum Riboflavin carrier protein antisera showed 14.391 % cytotoxic activity on HeLa cancer cells and standard drug used was Doxorubicin. HeLa cancer cell lines showed IC50 values of 33.31 ± 0.7 for Guinea pig serum Riboflavin carrier protein (RCP) antisera.

Keyword :

Riboflavin carrier protein (RCP) antisera, Guinea Pig Serum, HeLa cancer cells.
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