Abstract :
Background: To study the Prevalence of thrombocytopenia during pregnancy and its effect on pregnancy and neonatal
outcome. Methods: It was a prospective one year study of pregnancy with thrombocytopenia. The cause of
thrombocytopenia and feto-maternal outcomes in pregnancy with thrombocytopenia was studied. Results: Among 1450
deliveries, total 137 women were having thrombocytopenia in third trimester. The commonest etiology was gestational
thrombocytopenia (61%). Thrombocytopenia due to severe preeclampsia and HELLP syndrome in this study was
24%,Placental abruption 9(6.6%), PPH 6(4.3%), Wound hematoma 5(3.6%) were noted. Fetal complications – stillbirth
11(8%), low birth weight 14(10.21%), low APGAR 22(16.2%) and neonatal thrombocytopenia 6(4.3%). Thrombocytopenia
in pregnancy did not affect the mode of delivery and pre-term delivery rate. Conclusion: Feto-maternal complications with
thrombocytopenia depend primarily on the disease causing it. Gestational thrombocytopenia, preeclampsia, HELLP
syndrome, malaria, ITP and dengue were the common causes of thrombocytopenia in pregnant. Patients with GT and ITP
have better maternal and peri-natal outcomes as compared to preeclampsia and HELLP syndrome.
Keyword :
Peri-natal Outcome, Pregnancy, Thrombocytopenia