Abstract :
Introduction: Rapid distribution of bacteria in wound infection and their appropriate treatment with antibiotics are crucial for health care providers. Bangladesh is vulnerable to multi-drug-registrant antibiotics due to extensive antibiotic misuse and other factors. The purpose of the present study was to see the frequency and distribution of bacteria isolated from pus and sensitivity patterns among hospitalized patients.
Materials and Methods: A cross-sectional study was carried out from June 2020 to July 2021. The pus samples were collected from the patients who visited BIHS General Hospital, Dhaka. Isolation and Identification of bacteria were made by culture and biochemical test and antibiotic susceptibility test was done by disc diffusion method.
Results: The most common isolates were S.aureus. Gram-positive bacteria were mostly resistant to Penicillin, Cefoxitin, Ampicillin, Azithromycin, Cotrimoxazole, Cefuroxime, and Cepradine antibiotics. 57.1% of S.aureus and (100%) of S.epidermidis was Methicillin-resistant, AMPC β-Lactamase producing bacteria (52.2%), and ESBL are (13.0%).
Conclusion: Due to the abuse of antibiotics, Methicillin-resistant AMPC β-Lactamase, ESBL are increasing day by day. Our study found that MDR bacteria is increasing rapidly and which is a major problem. Therefore, Antibiotic susceptibility pattern testing is required before the use of antibiotics, and continuous monitoring of antibiotic sensitivity is needed to minimize resistance.
Keyword :
Antibiotic, Resistance, AMPC β- Lactamase, ESBL, Bacteria, Pus