Abstract :
Background: The aim of the present study was to investigate the drug
utilization pattern of antihypertensive drugs in pregnancy induced
hypertension.
Methods: A retrospective observational study was conducted by
department of Pharmacy practice in collaboration with the Department
of Obstetrics in a tertiary care hospital at Karnataka after taking
permission from the Institutional Review Board. WHO basic indicators
were indicators were used for studying the prescribing pattern of drugs.
The study involves collection and documentation of case sheets and
treatment charts of inpatients with a diagnosis of pregnancy induced
hypertension along with other co morbidities.
Results: Out of the total prescriptions studied the most commonly
prescribed antihypertensive was nifedipine , followed by labetalol and
methyldopa . Majority drugs prescribed were from category C and B.
Single drug therapy was prescribed in 77.01% patients. The use of fixed
dose combinations was low.
Conclusion: The incidence of single drugs therapy and two drugs was
high. Nifedipine was the commonly prescribed antihypertensive. None of
the prescribed drugs were from teratogenic category D and X.
Keyword :
Antihypertensives, Drug use indicators, Pregnancy induced hypertension,Pregnancy category of drugs