Abstract :
Prediabetes (intermediate hyperglycaemia) is a high-risk state for diabetes that is defined by glycaemic variables that are higher than normal, but lower than diabetes thresholds. 5-10% of people per year with prediabetes will progress to diabetes, with the same proportion converting back to normoglycaemia. Prevalence of prediabetes is increasing worldwide and experts have projected that more than 470 million people will have prediabetes by 2030. Observational evidence shows associations between prediabetes and early forms of nephropathy,chronic kidney disease, small fibre neuropathy, diabetic retinopathy, and increased risk of macrovascular disease. Tabak A.G. (2012). Multifactorial risk scores using non-invasive measures and blood-based metabolic traits, in addition to glycaemic vales, could optimise estimation of diabetes risk. For prediabetic individuals, lifestyle modification is the cornerstone of diabetes prevention, with evidence of a 40-70% relative-risk reduction.
Keyword :
Prediabetes, ADA, CDC, Risk score, Screening, Prevalence, Risk factors Intervention.