Abstract :
The aim of the present study was to investigate the phytochemical screening, anti-inflammatory activity from
the leaf of Borreria hispida by membrane stabilization test. The leaves were collected from different regions of Tamil
Nadu. The leaf extracts of Borreria hispida from five different solvents were investigated. The phytochemical
analysis revealed the presence of active ingredients such as phenols, flavanoids, saponins, alkaloids and terpenoids.
Total phenols, flavanoids, saponins, alkaloids and terpenoids were quantitatively estimated. The maximum total
phenol (33.2 mg GAE/g), flavanoid content (18.27 mg QE/g), Saponin (19.7 mg/g), alkaloid content (83.2 mg/g) and
total terpenoids (76.4 mg/g) were recorded from the ethanolic leaf extract of Borreria hispida. The leaf extracts were
evaluated by membrane stabilization test. The maximum % of inhibition of haemolysis of Borreria hispida was
found to be 81.9% at a dose of 12.5 mg/ml. The extract shows significant anti-inflammatory activity which supports
the traditional medicinal utilization of the plant.
Keyword :
Phytochemical screening, Anti-inflammatory, Membrane stabilization test.