Abstract :
The present work determine the phytochemical potential, antioxidant activity and enzyme inhibition activities of
crude extract of Gisekia Pharnaceoides Linn (Molluginaceae).Total phenolic content (TPC) and total flavonoid
content (TFC) of the plant extracts were in the range 5.56 ± 1.30--8.11 ± 1.249 mg gallic acid equivalent/g extract
and 4.33 ± 1.003--6.31 ± 0.022 mg rutin equivalent/g extract, respectively. Antioxidant actions of crude extracts
were evaluated by 1,1-diphenyl-2-picrylhydrazyl free radical (DPPH). The half-maximal inhibitory concentrations
(IC50) of the extracts of tyrosinase and α-glucosidase were expressively higher than the references kojic acid and
acarbose, respectively. These results suggest that the plant material possess moderate antioxidant activity and
thought-provoking inhibitory action against key enzymes that might be due to the existence of phytoconstituents,
thus supporting folkloric use.
Keyword :
Antioxidant, Phenolic, Flavonoid, Inhibition, Cholinesterase, Tyrosinase, α-Glucosidase, Gisekia Pharnaceoides