Abstract :
Introduction: The novel coronavirus is a single stranded RNA virus with spike proteins triggering an immune response leading to cytokine storm and coagulopathy. Pregnancy is an immunocompromised and hypercoagulable state, with predis position to severe illness. An insight into impact of COVID-19 in pregnancy is essential to combat its future.
Materials and Methods: This study was conducted at a tertiary care centre. Analytical study was conducted from the data collected regarding COVID-19 positive labour room admissions, deliveries and deaths during the second wave of pandemic.
Results: There was a discharge rate of 88.14% after safe delivery. Among COVID-19 maternal mortalities, most deaths were due to ARDS. Quick SOFA score was a good predictor for morbidity and mortality. Deranged coagulation profile and D-Dimer levels more than 500 ng/ml were good predictors of mortality. Silent hypoxia needs to be identified and corrected at admission. Delay in seeking medical advice was a major contributory risk factor.
Conclusion: Increasing awareness among public about seeking medical advice during early stages of disease. Early identification and treatment according to latest guidelines for a positive outcome. Making aware the policy makers regarding risk-benefits of vaccination in mothers can come a long way in changing the fate of COVID-19 in pregnancy.
Keyword :
COVID- 19, Pregnancy, Second wave, Vaccination.