Volume :

6

Issue :

2

Abstract :

Suspensions are coarse dispersions defined as a biphasic liquid dosage form of medicaments in which insoluble solid particles are suspended uniformly in a liquid. The size of the insoluble solid particles in liquid phase may exceed 0.1µm.Dispersed phase is also known as internal phase and continuous phase is also known as external phase. Present research work focuses on effect of suspending agents in diclofenac suspension. Both natural and synthetic suspending agents are used. The natural suspending agent is gelatin and synthetic suspending agent is carbopol. Different concentrations of gelatin (2%, 3%, and 4%) and carbopol ((2%, 3%, and 4%) was prepared. Six formulations with formulation code of F1, F2, F3, F4, F5, and F6 was formulated. The prepared suspensions are evaluated for viscosity,pH, sedimentation volume, degree of flocculation, particle size etc.