Abstract :
Introduction: Pseudomonas aeruginosa is a major cause of health care associated infections. It has natural resistance as well as acquired multidrug resistance to various antibiotics leading to increased morbidity and mortality, which lead to problematic condition and increased medical expenses. The main aim of this study was to study the resistance pattern of Pseudomonas aeruginosa isolated from samples received from surgical site infections and wound infections.
Materials and Methods: This study was conducted at Microbiology laboratory of Teerthanker Mahaveer Medical College and Research Centre. Pus and wound swab samples were collected from surgical site infections (SSIs) and wound infections. Samples were cultured on MacConkey and Nutrient agar and incubated at 37?C aerobically. Identification of Pseudomonas aeruginosa was done by using conventional method and antibiotic sensitivity was determined with automated Vitek2 compact system.
Results: From January 2021 to November 2021 during this study period, out of 117 positive samples 32 (27.35%) Pseudomonas aeruginosa were isolated. The susceptibility pattern showed the organism to be most commonly susceptible to Colistin, Doripenem, followed by Piperacillin/Tazobactam, Imipenem, Amikacin, and was less susceptible to Ciprofloxacin, Ceftazidime.
Conclusion: Presences of multidrug resistance strains have raised significant concern and judicious use of antibiotics is the only option to reduce drug resistance and preventing resistance against reserve antibiotics.
Keyword :
Antibiotic sensitivity Pattern, P aeruginosa, SSIs