Abstract :
Background: Papillary lesions of the breast encompass a wide spectrum of benign and malignant entities.
Cytological interpretation of these is difficult and they top the list of conditions with a risk of false-positive
diagnosis. Understanding the correlation of histologically confirmed benign and malignant papillary
neoplasm with demographic parameters and features of neoplasm will help to distinguish the different
lesions.
Aims and Objectives: To compare histologically confirmed benign and malignant papillary neoplasm
with demographic parameters and features of neoplasm
Materials and Methods: A retrospective study was performed from January 2010 to December 2015 in
the cytology section, Department of Pathology of a tertiary care and referral hospital including patients
diagnosed as papillary lesion on FNAC. Histopathological follow-up was available for total 44 cases. A
total of 44 breast aspirates and their corresponding histology were reviewed.
Results: Majority of the patients with benign and malignant neoplasm had age between 41-50 years (33%)
and 51-60 years. All patients with benign neoplasm were women whereas among patients with malignant
neoplasm 12 were women and one was a man. Benign papilloma, 36.3% cases showed cellular smear,
followed by 27.2% showed moderate cellularity. Malignant papillary lesions, cases showed both cellular
and moderate cellularity.
Conclusion: Papillary carcinoma is an infrequent histologic subtype of breast carcinoma. Cytological
diagnosis of the lesion is difficult due to overlap with benign entity and other mimics.
Keyword :
Histopathology, Malignant papillary neoplasm, Lesions.