Article type :
Review Article
Author :
Mahenigar ,, Ajay Mahajan, Kanwarjit Singh Asi, Vandana Sharma, Mahenigar ,, Ajay Mahajan, Kanwarjit Singh Asi, Vandana Sharma, Mahenigar ,, Ajay Mahajan, Kanwarjit Singh Asi, Vandana Sharma
Volume :
10
Issue :
3
Abstract :
Periodontal disease is a complex multifactorial disease. Progression and initiation of periodontal disease are related to multiple etiologic and risk factors, characterized by a disruption in the equilibrium between the host's immune response and the role of the human microbiome. The understanding of the pathogenesis of periodontal disease has improved over the past few years. Consequently, the main objective of periodontal treatment has recently transitioned toward reestablishing homeostasis within the oral microbiome and promoting a balanced interaction with the host's periodontal tissues. This review explores recent advancement in alternative therapeutic strategies and novel compounds that offer promising potential in the prevention and management of periodontal conditions.
Keyword :
Recent therapeutic targets, Periodontal diseases, Host modulation, Immunomodulation, Inflammasomes, Quorum sensing, Quorum quenching, Sclerostin, Anabolic agents.