Myelin Oligocytes Glycoprotein (MOG) antibody positive bilateral optic perineuritis in a young male treated with steroids and fingolimod


Article PDF :

Veiw Full Text PDF

Article type :

Case Report

Author :

Dhaivat Shah, Garima Vaishnav, Rahul Singh, Ravin Punamia, Tina Damani

Volume :

6

Issue :

4

Abstract :

A 25 year old male, chronic smoker presented with sudden diminution of vision and pain on ocular movement in both eyes. Fundus examination revealed both eyes optic disc swelling. Patient responded well to pulse dose intravenous Methylprednisolone (IVMP). MRI showed both eyes mild optic nerve sheath enhancement. Three month later, he came with blurring of vision in both eyes with right eye lateral rectus palsy. Atypical panel revealed Anti-MOG positive in serum. He was given IVMP and is started on oral Fingolimod, and is stable at present. We report a case of recurrent bilateral optic perineuritis with seropositive MOG autoantibody and abducens nerve palsy.

Keyword :

 Optic perineuritis, Myelin Oligocytes Glycoprotein antibody, Fingolimod,  Optic nerve sheath enhancement pulse dose steroid abducens nerve palsy.
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