Volume :
2
Issue :
2
Abstract :
A simple, fast and reliable Spectrophotometric method was developed for determination of Lamivudine in bulk and pharmaceutical formulation. Spectrophotometrically, Lamivudine was determined by measuring the maximum absorption at 280nm. Analytical Calibration curves were linear within a concentration range from 2 to 10µg/ml. The developed method was applied to directly and easily to the analysis of the pharmaceutical tablet preparations. %R.S.D was found to be 1.20(Lamivir HBV 100 mg Tablet) respectively. The percentage recoveries were100- 104% for given method. The method was completely validated. The results showed that this method can be used for rapid determination of Lamivudine in pharmaceutical tablet formulation with linearity, precision, accuracy specificity.