Male breast carcinoma- with numerous histological patterns - an interesting case report


Article PDF :

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Article type :

Case Report

Author :

Sankappa P. Sinhasan, Subashini R, Ramachandra V Bhat

Volume :

5

Issue :

2

Abstract :

Male Breast Carcinoma (MBC) is a rare condition accounting for risk factor includes hormonal imbalance, Klinefelter syndrome, testicular disorders, radiation exposure, alcoholism and antiandrogenic medication. MBC clinically manifests as painless palpable mass sometimes masquerading gynecomastia. Compared with female breast cancer, male breast carcinoma presents slightly older age at diagnosis with large tumor size and most of the tumors hormone receptor positive. We come across chronic alcoholic male presented with fungating growth over left breast. Cytology revealed neuroendocrine type of infiltrating ductal carcinoma cells, whereas biopsy showed various histological patterns in sections from different areas making this case interesting one. Immunohistochemically, it was positive for estrogen and progesterone receptor but negative for Her2neu marker.

Keyword :

 Male Breast Carcinoma, Comedocarcinoma, Neuroendocrine, Cribriform, Schirrous, Mucinous.
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