Author :
Venkatesan K, Vijay Narayanan S, Iniya R, Rajalekshmi M
Volume :
3
Issue :
2
Abstract :
Background: Adequate analgesia following caesarean section decreases morbidity, ambulation, improves patient outcome and facilitates care of the newborn baby. Intrathecal Magnesium, an NMDA antagonist has been shown to prolong analgesia without significant side effect in healthy parturients. We therefore studied the effect of adding intrathecal Magnesium sulphate to Bupivacaine, Fentanyl in patient with mild pregnancy induced hypertension undergoing caesarean section.
Aim: To study and compare the effect of added Fentanyl 0.5cc (25 mcg) & Magnesium sulphate 0.1cc 50% (50mg) to 0.5% 2cc (10mg) Bupivacaine, in patients with pregnancy induced hypertension (PIH) undergoing elective Caesarean section under spinal anesthesia.
Materials and Methods: 60 patients undergoing elective caesarean section under spinal anaesthesia were randomly divided into three groups. Control group (N=20) received 0.5% 2cc (10mg) Inj.bupivacaine 0.6cc normal saline. Fentanyl group (N=20) received 0.5% 2cc (10mg) Inj.bupivacaine 0.5cc (25micgm) Inj.fentanyl 0.1cc normal saline. Magnesium sulphate group (N=20) received 0.5% 2cc (10mg) Inj.bupivacaine 0.5cc (25mcg) Inj.fentanyl 0.1cc 50% (50mg) magnesium sulphate. Onset, duration and recovery of sensory and motor block, duration of spinal anaesthesia, APGAR score and post operative analgesia duration were studied. Statistical analysis was done using univariate analysis, ANOVA and two group âTâ test. p