Abstract :
Introduction: Vitamin D deficiency (VDD) is a global health concern. Previous studies have shown
significant deficiency of vitamin D in hypothyroid subjects compared to euthyroid subjects with higher
deficiency in the female population compared to males.
Materials and Methods: A total of 70 adult females aged 41-65 years were enrolled in the study after
obtaining their informed written consent. They were categorized into 2 groups consisting 35 Hypothyroid
cases and 35 Euthyroid controls respectively. Serum vitamin D, TSH, fT3 and fT4 levels were assessed by
chemiluminescent immunoassay (CLIA). VDD was designated at levels lower than 20 ng /ml and Vitamin
D insufficiency (VDI) at level between 20 ng /ml - 30 ng /ml. Levels > 30 ng /ml were stated as vitamin D
sufficiency state. Level Results: The study shows significantly reduced levels of Vitamin D in hypothyroid female subjects
compared to age and gender matched euthyroid controls. Majority of hypothyroid subjects and euthyroid
controls were falling in VDD range rather than VDI range. We also observe that hypothyroid subjects were
more in VDD category as compared to euthyroid subjects.
Keyword :
Vitamin D Deficiency, Hypothyroidism, Thyroxine, Thyrotropin.