Abstract :
Metastatic malignancies of the oral cavity are a rare phenomenon, accounting for only about 1% of all oral malignancies. The metastatic tumor cells may affect the jaw bones or the oral soft tissues or even both. The primary tumors commonly implicated in oral metastasis are usually from the lungs, breast, kidney and bone. In 25% of cases, oral metastasis indicates the first sign of metastatic spread and in 23% it may be the first evidence of dissemination of malignancy from its primary site. Lung cancer is the most commonly diagnosed major cancer in the world that mainly arises from the epithelial cells such as neuro -endocrine cells, club cells, and neuro – epithelial cells. In this review, we have highlighted the various predisposing factors and propose hypothetical pathways of lung carcinoma metastasizing to the different areas of the body including the oral cavity.
Keyword :
Metastasis, Lung. Oral cavity. Hematogenous, Lymphatic.