Abstract :
Objectives: To identify the proportion of children on intermittent clobazam therapy developing febrile seizure recurrence and to assess the risk factors of febrile seizure recurrence in children.
Design: Descriptive follow up study.
Study setting: Children between 6 months to 5 years admitted in Govt.TDMCH for seizures associated with fever.
Materials and Methods: Children presenting with acute febrile seizures are started on intermittent clobazam therapy. The risk factors were assessed and study group is followed up for a period of one year. Data were analyzed using computer software SPSS. Data are expressed in its frequency and percentage as well as mean and standard deviation. To elucidate the associations and comparisons between different parameters, Chi square(X2) test was used as non-parametric test.
Results: Out of the 80 children followed up 28 children developed recurrence. Those who took clobazam had considerable reduction in recurrence (8.3% in clobazam group compared to 56.8% in those who were not on intermittent clobazam therapy. Complex febrile seizures (Odds ratio of 16.5 and p value
Keyword :
Febrile seizure, Recurrence, Clobazam.