In vivo study wound healing potential (incision) of herbal formulation


Volume :

2

Issue :

4

Abstract :

Lygodium flexuosum is a climbing fern it is the sole genus in the family Lygodiaceae, though it is included in the family Schizaceae by some botanist. It occurs on mangrove and had tree dominated habitat sub division is petridophyte and had life form of cryptophytes category. It is commonly epiphytically grows on moss covered tree trunks, branches a lithophytes on shady boulders along with moss and in Thailand its habitat is in abundance. The present study has demonstrated that an ethanol extract of Lygodium flexuosum leaves extract has properties that render it capable of promoting accelerated wound healing activity compared with the controls. Wound contraction increased tensile strength, increased hydroxyproline content. It is used in external applications for rheumatism, sprains, scabies, eczema and cut wounds, they are reported to be particularly useful for carbuncles, reduce inflammation and acts as panacea for wounds, treat ulcer, various respiratory diseases, general disorders, muscles sprains. In pharmacological studies Wound healing activity was done and it was observed that topically administered drugs are effective in faster wound contraction due to the larger availability at the wound site. A significant increase in wound contraction was seen in both doses of ELF compared to control. Hence it appears that ELF has prohealing effect.
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