Volume :
1
Issue :
3
Abstract :
Physalis angulata L. belongs to the family Solanaceae found in southern region of India, which is used in the treatment of variety of illnesses, such as malaria, asthma, hepatitis, dermatitis and rheumatism. The qualitative phyto-chemical screening showed the presence of steroids, flavonoids, and alkaloids. The Aqueous, Ethanol and Methanol fractions of the leaves of Physalis angulata L. were subjected to In vitro Anti-inflammatory activity by HRBC membrane stabilization method and in vitro anti-arthritic activity by protein denaturation method in various concentrations i.e. 10, 62.5, 125, 250, 500, 1000, 2000µg/ml. All the extracts showed positive response as compared to standard Diclofenac sodium. The Ethanol extract showed maximum activity. The order of effect of different extracts were represented as follows Ethanol > Water > Methanol.