Abstract :
Objective: To observe impact of percutaneous coronary intervention in patients with mild renal dysfunction and its impact on inhospital
outcome.
Patients and Methods: This is descriptive case series study conducted at department of Cardiology at Liaquat University
Hospital, Jamshoro From 11-02-2015 to 11-08-2015. Total 50 patients who satisfy KDOQI criteria for mild renal disease and
underwent PCI were included in the study. Contrast medium was injected. Pre and post PCI level of serum creatinine was
estimated. GFR was calculated by CKD-EPI equation. Patient was discharge after seven days and followed after one week.
Descriptive statistics were calculated. Chi-square and T-test was used as applicable. The p-value ≤0.05 was considered as
significant.
Results: There were 46 male and 4 female patients. Mean age was 50.48±6.61 years. 24% PCI for RCA & LAD, 42% for LAD,
30.0% for RCA, and 4.0% for LCx was done. The mean volume of contrast used was 158.20±30.88 ml. Mean difference of urea
at base line and after 72 hrs is significant with P-value 0.000. Mean difference of creatinine at base line and after 72 hrs is not
significant with P-value 0.280 but it was significant between after 24 hrs and after 72 hrs with P-value 0.023. Acute renal failure
was 24.0%, hemodialysis was 6.0% cases, and in 70.0% cases no remarkable change in renal function was observed.
Conclusion: Patients with baseline elevation of serum Cr-concentration were at risk of ARF after PCI and increased in risk of
in-hospital development of renal disease.
Keyword :
Percutaneous Coronary Intervention, Mild Renal Dysfunction, In-Hospital Outcome