Abstract :
Background: Polycystic ovary syndrome (PCOS) is a prevalent endocrine disorder affecting women of reproductive age, characterized by oligo-menorrhea, hyper-androgenism, and metabolic disturbances. Vitamin D deficiency is common in PCOS patients and may exacerbate symptoms. This study aims to investigate the relationship between body mass index (BMI) and vitamin D levels in PCOS patients in a North Indian population.Materials and Methods: A prospective observational study was conducted at T.S. Mishra Medical College and Hospital from November 2023 to November 2024. A total of 156 patients aged 18-45 years with PCOS were enrolled based on modified Rotterdam criteria. Blood samples were analyzed for metabolic parameters, including serum vitamin D levels, and BMI was calculated. Statistical analysis was performed using SPSS 25.0.Results: The mean age of participants was 23.3 ± 1.4 years, with a mean BMI of 26.72 ± 1.6 kg/m2. Vitamin D deficiency (30 ng/ml). No significant association was found between BMI categories and vitamin D levels (p=0.06719). However, significant differences were noted in metabolic parameters, with higher fasting insulin, DHEAS, and testosterone levels in vitamin D deficient patients (p
Keyword :
PCOS, Hyper-androgenism, BMI, DHEAS, Vitamin D, Fasting insulin.