Abstract :
Background: The histopathological diagnosis of abnormal uterine bleeding (AUB) shows spectrum of patterns and pathologist plays a vital role in the reporting of endometrium and differentiating non-neoplastic lesion from neoplastic lesions, early detection of precursor lesions and exclusion of malignancy. The aim of this study is to study the spectrum of endometrial patterns in women with AUB and to correlate with the different age groups.
Materials and Methods: 256 samples of endometrial samples in women with AUB are received from the gynaecology department, processed and stained with hematoxylin & eosin and subjected to histopathological examination.
Results: The peak incidence is observed in the age group of 51-60 years. The most common histomorphological pattern is proliferative pattern. 60 cases (23.43%) show endometrial hyperplasia out of which 6 cases show atypia. Only 1 case(0.39%) of endometrial carcinoma reported overall and reported in postmenopausal age. Pill endometrium and chronic endometritis are not reported in postmenopausal age group and all 3 cases of atrophic endometrium are reported in postmenopausal age group.
Conclusion: AUB significantly affects the quality life of women and leads to anemia. Hence histopathological examination should be considered which plays a critical role in early diagnosis of endometrial pathology and to provide appropriate gynaecological management.
Keyword :
Abnormal uterine bleeding, AUB, Biopsy, Endometrium, Histopathology.